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  • Cancer & Signaling Discussion Group

    Cancer research has revealed that complex systems of molecular pathways drive tumor formation. By understanding these pathways, scientists hope to identify molecular targets within them that would be receptive to drugs in ways that could interrupt cancer progression.

    The Cancer & Signaling Discussion Group provides a forum for exploring the molecular networks that ensure proper cell cycle progression, and how alterations in these networks modulate gene expression, cause mutations, and lead to carcinogenesis. Meetings of the group focus on specific themes related to signal transduction dysregulation in oncogenesis, and cover basic, clinical, and diagnostic aspects of the field.

  • Events

    Wednesday, March 17, 2010 | 1:00 PM - 5:00 PM

    The Hedgehog Pathway in Cancer

    Speakers: Andy McMahon (Harvard University), Kenneth Olive (Columbia University), Robert Yauch (Genentech, Inc.)

    The Hedgehog Signaling Pathway regulates processes essential for embryo development, offering a novel approach to the treatment of some cancers. This meeting reviews its role in disease pathogenesis and discusses potential therapeutic opportunities.

  • Steering Commitee

    David Epstein, PhD

    OSI Pharmaceuticals

    Senthil Muthuswamy, PhD

    Cold Spring Harbor Laboratory

    Pier Paolo Pandolfi, MD, PhD

    Harvard Medical School

    Nicholas Tonks, PhD

    Cold Spring Harbor Laboratory

    George Zavoico, PhD
    Asher Zilberstein, PhD

    Sanofi-Aventis


  • Sponsors

    • Sanofi
    • OSI

    Mission Partner support for the Frontiers of Science program provided by:

    • Johnson & Johnson

    Get more information about how you can sponsor a discussion group.

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